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[妊娠高血压综合征症状女性临床评估中的细胞免疫某些因素]

[Certain factors of cellular immunity in clinical evaluation of women with EPH gestosis symptoms].

作者信息

Malinowski A, Szpakowski M, Tchórzewski H, Zeman K, Kowalczyk T, Oszukowski P

机构信息

Katedry Połoznictwa i Ginekologii WAM, Lodzi.

出版信息

Ginekol Pol. 1992;63(7):324-8.

PMID:1305136
Abstract

The applicability of clinical examination was studied in women with symptoms of medium-advanced or advanced primary gestosis of subpopulation of T lymphocytes (CD3+, CD4+, CD8+) in the peripheral blood. Also studied was the usefulness of the proliferative activity of lymphocytes in in vitro cultures: spontaneous and mitogenic (PHA, ConA, PWM)--in the environment of fetal calf serum (FCS) and autologous sera: heat-inactivated and heat-non-inactivated. It has observed that the percentages of particular T Lymphocyte subpopulations and the proportion of CD4+ lymphocytes to CD8+ lymphocytes in the peripheral blood and the mitogenic activity of the heat-non in activated autologous serum in the test of lymphocyte spontaneous blastic transformation reveal a correlation with an enhancement of particular clinical symptoms of EPH gestosis and with the birth condition of newborns.

摘要

对患有中晚期或晚期原发性妊娠中毒症的女性进行了临床检查的适用性研究,研究对象为外周血中T淋巴细胞亚群(CD3+、CD4+、CD8+)。还研究了淋巴细胞在体外培养中的增殖活性的有用性:自发和促有丝分裂(PHA、ConA、PWM)——在胎牛血清(FCS)和自体血清环境中:热灭活和热未灭活。观察到外周血中特定T淋巴细胞亚群的百分比以及CD4+淋巴细胞与CD8+淋巴细胞的比例,以及热未灭活自体血清在淋巴细胞自发母细胞转化试验中的促有丝分裂活性,与EPH妊娠中毒症特定临床症状的加重以及新生儿的出生状况存在相关性。

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1
[Certain factors of cellular immunity in clinical evaluation of women with EPH gestosis symptoms].[妊娠高血压综合征症状女性临床评估中的细胞免疫某些因素]
Ginekol Pol. 1992;63(7):324-8.
2
Essential edema-proteinuria-hypertension (EPH) gestosis and gestosis superimposing pre-existing renal disease: comparison of cellular immunity parameters.原发性水肿-蛋白尿-高血压(EPH)妊娠中毒症与妊娠中毒症合并原有肾脏疾病:细胞免疫参数比较
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