Echeverría R F, Carbajal H A, Salazar M R, Riondet B, Rechifort V, Quaini M
Sección Hipertensión Arterial, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina.
Medicina (B Aires). 1992;52(2):145-9.
In 1985 we investigated the prevalence of high normal blood pressure in 6387 inhabitants (range 15-75 years old) of the city of La Plata and its progression to arterial hypertension after four years. High normal blood pressure was defined as a systolic blood pressure (BP) < 140 mmHg and diastolic BP between 85-89 mmHg (average value of two measurements) on one occasion. Arterial hypertension was defined as a systolic BP > or = 140 mmHg and/or diastolic BP > or = 90 mmHg, both as an average of two measurements on two occasions. High normal BP prevalence was 6.62%, being higher in men than in women (p < 0.0005, Table 1). General progression to hypertension was 41.79%, being higher in the older individuals (p < 0.0005). Of the 423 individuals with high normal BP (Table 2), 268 (63.36%) were found in 1989 (Table 3). They had an incidence of hypertension of 10.45% per year, also higher in older subjects (Table 4). There were no differences between sexes. Subjects with high normal BP who subsequently developed hypertension had higher systolic BP in 1985 than those who remained normotensive (p < 0.001, Table 5). Most of them progressed to mild diastolic hypertension (29.48%) or borderline isolated systolic hypertension (6.72%, Fig. 1). In this study, progression to arterial hypertension was higher than that reported in similar studies for general population in other countries.
1985年，我们对拉普拉塔市6387名居民（年龄在15至75岁之间）进行了高正常血压患病率调查，并观察了四年后其向动脉高血压的进展情况。高正常血压定义为一次测量时收缩压（BP）<140 mmHg且舒张压BP在85 - 89 mmHg之间（两次测量的平均值）。动脉高血压定义为收缩压BP≥140 mmHg和/或舒张压BP≥90 mmHg，均为两次测量的平均值，且测量在两个不同时间点进行。高正常血压患病率为6.62%，男性高于女性（p<0.0005，表1）。向高血压的总体进展率为41.79%，老年人中更高（p<0.0005）。在423名高正常血压个体中（表2），1989年发现了268名（63.36%）（表3）。他们每年的高血压发病率为10.45%，老年受试者中也更高（表4）。性别之间无差异。随后发展为高血压的高正常血压受试者在1985年的收缩压高于仍为正常血压的受试者（p<0.001，表5）。他们中的大多数进展为轻度舒张期高血压（29.48%）或临界单纯收缩期高血压（6.72%，图1）。在本研究中，向动脉高血压的进展高于其他国家针对普通人群的类似研究报告的进展情况。
