Papotti M, Gherardi G, Eusebi V, Pagani A, Bussolati G
Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italy.
Virchows Arch A Pathol Anat Histopathol. 1992;420(1):103-8. doi: 10.1007/BF01605991.
Four cases of oat cell (neuroendocrine) carcinoma of the breast are reported. Three patients died within 15 months of the diagnosis and the fourth patient is alive after 44 months. Histochemical, ultrastructural and mRNA markers of endocrine differentiation were present in three cases. These tumours show histological similarities to breast metastases of bronchial oat cell carcinoma, but a distinguishing feature is the presence of in situ ductal lesions. It appears that the breast is a further site which has to be added to the long list of extrapulmonary oat cell carcinomas.
本文报告了4例乳腺燕麦细胞（神经内分泌）癌。3例患者在诊断后15个月内死亡，第4例患者在44个月后仍然存活。3例病例中存在内分泌分化的组织化学、超微结构和mRNA标志物。这些肿瘤在组织学上与支气管燕麦细胞癌的乳腺转移瘤相似，但一个显著特征是存在原位导管病变。看来乳腺是必须添加到肺外燕麦细胞癌众多发病部位清单中的又一部位。
