Phillips Mary L, Sierra Mauricio
Institute of Psychiatry, Denmark Hill, London, UK.
Stress. 2003 Sep;6(3):157-65. doi: 10.1080/1025389031000138538.
Clinical reports of depersonalization suggest that attenuated emotional experience is a central feature of the condition. Patients typically complain of emotional numbness and some patients ascribe their feelings of unreality to a lack of affective "colouring" in things perceived. Recent neuroimaging and psychophysiological studies support these assumptions as they show both attenuated autonomic responses in depersonalization, and decreased activity within neural regions important for the generation of affective responses to emotive stimuli. Furthermore, findings from neuroimaging studies indicate increased prefrontal cortical activity in depersonalised patients, particularly within regions associated with contextualization and appraisal of emotionally-salient information rather than mood induction per se. Taken together, these finding suggest that symptoms of depersonalization, and in particular emotional numbing, may be related to a reversal of normal patterns of autonomic and neural response to emotive stimuli.
人格解体的临床报告表明，情感体验减弱是该病症的核心特征。患者通常抱怨情感麻木，一些患者将他们的不真实感归因于所感知事物缺乏情感“色彩”。最近的神经影像学和心理生理学研究支持了这些假设，因为它们显示人格解体患者的自主反应减弱，以及对情感刺激产生情感反应至关重要的神经区域内的活动减少。此外，神经影像学研究结果表明，人格解体患者的前额叶皮质活动增加，特别是在与对情感突出信息进行情境化和评估相关的区域，而不是情绪诱导本身。综上所述，这些发现表明人格解体症状，尤其是情感麻木，可能与对情感刺激的自主和神经反应的正常模式逆转有关。
