Gillam D G, Newman H N, Davies E H, Bulman J S
Department of Periodontology, University of London, UK.
J Clin Periodontol. 1992 Mar;19(3):197-201. doi: 10.1111/j.1600-051x.1992.tb00639.x.
2 strontium chloride hexahydrate-containing dentifrices (SCH), similar except for their respective abrasive systems, were compared in a 2-month randomised double-blind parallel clinical study to evaluate their comparative effectiveness in terms of cervical dentinal hypersensitivity. 2 groups of 20 subjects, each with cervical dentinal hypersensitivity, were evaluated for tactile sensitivity by Yeaple probe, air sensitivity using a dental air syringe and subjective perception of pain by means of a visual analogue scale. There was no difference between the dentifrices as regards reduction of cervical dentinal hypersensitivity at each time point. The response to both dentifrices was evident within 4 weeks of use and the degree of improvement increased throughout the 8-week study period. The results support the conclusion that changing the abrasive component of SCH dentifrices did not significantly increase or decrease the (desensitizing) activity of the original product.
在一项为期2个月的随机双盲平行临床研究中，对2种除各自研磨系统外其他方面均相似的含六水合氯化锶牙膏（SCH）进行了比较，以评估它们在缓解颈部牙本质过敏方面的相对有效性。将2组各20名患有颈部牙本质过敏的受试者，通过Yeaple探针评估触觉敏感性，使用牙科气枪评估空气敏感性，并通过视觉模拟量表评估疼痛的主观感受。在每个时间点，两种牙膏在减轻颈部牙本质过敏方面没有差异。在使用4周内，两种牙膏均有明显效果，并且在整个8周的研究期间改善程度不断增加。结果支持以下结论：改变SCH牙膏的研磨成分不会显著增加或降低原产品的（脱敏）活性。
