Caniglia M, Elia L
Divisione di Malattie Infettive, Ospedale del Bambino Gesù di Roma.
Clin Ter. 1992 Feb;140(2):149-54.
VAHS (virus associated hemophagocytic syndrome) is a severe clinical and biological condition associated with certain menacing viral infections. It has been observed in patients with manifest immunodeficiency but also in previously apparently healthy children. Epstein-Barr virus (EBV) infection, although it is sometimes unrecognized and insidious, is one of the etiologies to be considered. Differential diagnosis with other causes of macrophage activation is a delicate task in pediatrics. Better understanding of the pathophysiology of the syndrome offers interesting therapeutic prospects.
病毒相关性噬血细胞综合征（VAHS）是一种与某些严重病毒感染相关的严重临床和生物学病症。在有明显免疫缺陷的患者中观察到过该病症，但在之前看似健康的儿童中也有发现。爱泼斯坦 - 巴尔病毒（EBV）感染虽然有时难以识别且隐匿，但也是需要考虑的病因之一。在儿科中，与巨噬细胞活化的其他原因进行鉴别诊断是一项棘手的任务。对该综合征病理生理学的更好理解提供了有趣的治疗前景。
