[通过检测唾液中抗甲型肝炎病毒 IgM 进行甲型肝炎诊断的研究]
[Study on diagnosis of hepatitis A by testing salivary IgM anti-HAV].
作者信息
Wang Y
机构信息
Hangzhou Health and Anti-epidemic Station, Zhejiang Province.
出版信息
Zhonghua Liu Xing Bing Xue Za Zhi. 1992 Feb;13(1):9-11.
The use of salivary samples to diagnose acute hepatitis A was investigated. Result indicated that IgM anti-HAV can be reliably detected in saliva of 58 cases with acute hepatitis A and 9 cases with mixed infection of hepatitis A and B. It is not present in saliva of individuals without recent hepatitis A including 84 cases with acute hepatitis B, 30 cases of hepatitis non A non B and 10 healthy individuals. It was suggested that use of salivary samples to diagnose hepatitis A was specific. It's concluded that saliva is a convenient and satisfactory alternative to serum for the clinical diagnosis and epidemiological investigation of hepatitis A infection.
对使用唾液样本诊断急性甲型肝炎进行了研究。结果表明，在58例急性甲型肝炎患者和9例甲型与乙型肝炎混合感染患者的唾液中能可靠检测到抗甲型肝炎病毒免疫球蛋白M（IgM anti-HAV）。在近期无甲型肝炎的个体的唾液中未检测到，这些个体包括84例急性乙型肝炎患者、30例非甲非乙型肝炎患者和10名健康个体。提示使用唾液样本诊断甲型肝炎具有特异性。结论是，对于甲型肝炎感染的临床诊断和流行病学调查，唾液是一种方便且令人满意的替代血清的样本。
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