Taccagni G L, Terreni M R, Rovere E, Villa E, Cantaboni A
Department of Pathology, University of Milan, Italy.
Ultrastruct Pathol. 1992 May-Jun;16(3):291-302. doi: 10.3109/01913129209061358.
The report describes a case of anaplastic large cell Ki-1 lymphoma of the stomach with a rapidly fatal course observed in a 28-year-old woman. By electron microscopy the neoplastic cells presented long projections of the cytoplasmic membrane arranged uniformly along all the cell circumference. The morphology and distribution of these projections were characteristic, and the term villopodial is proposed for them. A review of the literature revealed 18 cases of lymphoma and 7 cases of nonlymphoid neoplasms composed of cells with projections similar to those observed in the present case. It is suggested that such tumors be denominated villopodial lymphomas and villopodial tumors. The present case is the first anaplastic large cell Ki-1 lymphoma with villopodial projections reported in the literature.
该报告描述了一名28岁女性胃间变性大细胞Ki-1淋巴瘤病例，病程进展迅速并导致死亡。通过电子显微镜观察，肿瘤细胞呈现出细胞膜的长突起，沿整个细胞周长均匀排列。这些突起的形态和分布具有特征性，为此提出了“绒毛足样”这一术语。文献回顾显示，有18例淋巴瘤和7例非淋巴样肿瘤，其细胞具有与本病例中观察到的类似突起。建议将此类肿瘤命名为绒毛足样淋巴瘤和绒毛足样肿瘤。本病例是文献中报道的首例具有绒毛足样突起的间变性大细胞Ki-1淋巴瘤。
