Latham P D, Athanasou N A, Woods C G
Nuffield Department of Orthopaedic Surgery, Nuffield Orthopaedic Centre, Headington, Oxford, UK.
Arch Orthop Trauma Surg. 1992;111(3):183-6. doi: 10.1007/BF00388097.
This is a case report of a tumour which showed all the histological features of fibrous dysplasia without any features of high-grade malignancy, yet had become locally aggressive, causing cortical erosion and extension into soft tissue. Fibrous dysplasia is a well-recognised entity that encompasses monostotic lesions, polyostotic involvement and Albright's syndrome [6, 8]. Lesions in bone usually spare the epiphysis before puberty, but often involve the epiphyseal area after maturity and can progress during adult life [3]. Unless cystic [6, 10] or malignant change [7, 10, 11] occurs, fibrous dysplasia usually remains contained within bone.
这是一例肿瘤病例报告，该肿瘤具有骨纤维发育不良的所有组织学特征，无任何高级别恶性特征，但已具有局部侵袭性，导致皮质骨侵蚀并延伸至软组织。骨纤维发育不良是一种公认的疾病，包括单骨病变、多骨受累及奥尔布赖特综合征[6, 8]。骨病变在青春期前通常不累及骨骺，但在成熟后常累及骨骺区域，且在成年期可能进展[3]。除非发生囊性变[6, 10]或恶变[7, 10, 11]，骨纤维发育不良通常局限于骨内。
