缺氧、心肌肥大及饮食对大鼠心肌鸟氨酸脱羧酶活性的影响。
The effects of hypoxia, hypertrophy, and diet on rat myocardial ornithine decarboxylase activity.
作者信息
Krelhaus W, Gibson K, Harris P
出版信息
Recent Adv Stud Cardiac Struct Metab. 1975;7:85-90.
We have shown that there is a highly significant difference between right and left ventricular ornithine decarboxylase activity. The left ventricle had a much higher activity compared with the right ventricle. A restricted diet caused a decrease in ornithine decarboxylase activity after 24 hr. Hypoxia caused a depression of the ornithine decarboxylase activity during the first 2 days of the experiment. In the hypertrophied right ventricle there was an initial decrease in ornithine decarboxylase after 24 hr and then a gradual increase in ornithine decarboxylase activity during the 7 days of the experiment. The increase in ornithine decarboxylase activity became significant when an increase in tissue weight became apparent.
我们已经表明，右心室和左心室鸟氨酸脱羧酶活性之间存在高度显著差异。与右心室相比，左心室的活性要高得多。限制饮食在24小时后导致鸟氨酸脱羧酶活性降低。缺氧在实验的前两天导致鸟氨酸脱羧酶活性降低。在肥厚的右心室中，24小时后鸟氨酸脱羧酶最初降低，然后在实验的7天内鸟氨酸脱羧酶活性逐渐增加。当组织重量明显增加时，鸟氨酸脱羧酶活性的增加变得显著。
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