Rettig G, Antony P, Gibson K, Harris P
Res Commun Chem Pathol Pharmacol. 1979 Jan;23(1):195-8.
A small, but not significant, decrease in ornithine decarboxylase activity occurred in isolated hearts during one hour of recirculating perfusion with Krebs-Henseleit solution. A significantly greater decrease occurred with a non-recirculating system. Ornithine decarboxylase activity was the same in the working heart preparation as in the non-working preparation. It is concluded that a substance, necessary for the maintenance of ornithine decarboxylase, is removed during perfusion. The nature of the mechanical activity of the heart did not appear to be a determining factor.
在用克雷布斯 - 亨泽莱特溶液进行一小时循环灌注期间，离体心脏中的鸟氨酸脱羧酶活性出现了轻微但不显著的下降。在非循环系统中，下降幅度明显更大。工作心脏制剂中的鸟氨酸脱羧酶活性与非工作制剂中的相同。由此得出结论，在灌注过程中，维持鸟氨酸脱羧酶所需的一种物质被去除了。心脏机械活动的性质似乎不是一个决定性因素。
