Bukachevsky R P, Pincus R L, Shechtman F G, Sarti E, Chodosh P
Department of Otolarygnology-Head and Neck Surgery, New York Eye & Ear Infirmary, New York Medical College, New York.
Head Neck. 1992 Jan-Feb;14(1):44-8. doi: 10.1002/hed.2880140110.
Primary synovial sarcoma is an unusual tumor of the head and neck. Fewer than 75 cases have been reported in the literature. We have treated 7 additional cases; 3 in the hypopharynx, 2 in the parapharyngeal space, 1 in the oral pharynx and 1 in the posterior triangle of the neck. An enlarging cervical mass, voice change, and dysphagia were among the presenting complaints. CT revealed solitary nonhomogenous tumors from 3 to 7 cm in diameter. Microscopically, all cases showed a biphasic cellular pattern verified by immunohistochemical staining. Multimodality treatment consisted of surgery and postoperative radiation therapy with 3 patients receiving chemotherapy. Although the original pathology report was incorrect in 3 cases, clinical suspicion for synovial sarcoma ensured proper diagnosis.
原发性滑膜肉瘤是一种不常见的头颈部肿瘤。文献报道的病例少于75例。我们又治疗了7例；3例位于下咽，2例位于咽旁间隙，1例位于口咽，1例位于颈后三角。主要症状包括颈部肿块增大、声音改变和吞咽困难。CT显示直径3至7厘米的孤立性不均匀肿瘤。显微镜下，所有病例均显示双相细胞模式，经免疫组化染色证实。多模式治疗包括手术和术后放疗，3例患者接受了化疗。尽管3例患者的原始病理报告有误，但对滑膜肉瘤的临床怀疑确保了正确诊断。
