Steven F S, Reid H
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester, U.K.
Anticancer Res. 1992 Jul-Aug;12(4):1179-82.
Tumour cells and certain normal cells in wax embedded brain sections possess active isoenzymic forms of a cell surface protease. The normal isoenzymic forms are recognised by protease inhibitors present in normal serum; the tumour isoenzyme remains active after exposure to serum. Fluorescent location of cells possessing active isoenzyme after serum treatment reveals the tumour cells in these sections.
