Stewart J D, Low P A, Fealey R D
Montreal Neurological Institute, Quebec, Canada.
Muscle Nerve. 1992 Jun;15(6):661-5. doi: 10.1002/mus.880150605.
The purpose of this study was to evaluate sweating and cardiovascular autonomic function in patients with distal small fiber neuropathy (DSFN). Sweat testing by the quantitative sudomotor axon reflex test was abnormal in 32 of 40 (80%) patients. The thermoregulatory sweat test was abnormal in 18 of 25 (72%) patients; one or both tests were abnormal in 36 of 40 (90%). Minor heart rate abnormalities were present in 11 of 40 (28%) patients. We conclude that, in patients with DSFN: (a) the sympathetic sudomotor fibers are frequently affected, and that evaluation of sweating is a useful diagnostic test; (b) that the autonomic nerves controlling heart rate are less affected.
本研究的目的是评估远端小纤维神经病变（DSFN）患者的出汗情况及心血管自主神经功能。通过定量汗腺轴突反射试验进行的汗液测试显示，40例患者中有32例（80%）异常。25例患者中有18例（72%）体温调节汗液测试异常；40例患者中有36例（90%）一项或两项测试异常。40例患者中有11例（28%）存在轻微心率异常。我们得出结论，在DSFN患者中：（a）交感汗腺纤维经常受到影响，出汗评估是一项有用的诊断测试；（b）控制心率的自主神经受影响较小。
