Tiku M L, Beutner K R, Carmody P, Sultz H A, Kaul B L, Ogra P L
J Clin Microbiol. 1976 May;3(5):469-73. doi: 10.1128/jcm.3.5.469-473.1976.
The health care personnel (HCP) of an institution for the mentally handicapped were serially tested for the presence of hepatitis B surface antigen (HBSAg) and antibody over a period of 1.5 years. HBSAg was present in 1.8% and anti-HBS in 20.8% of HCP. The prevalence of seropositive HCP appeared to be related to the age and the prevalence of seropositive residents cared for by the HCP. The occurrence of seropositivity was higher in the HCP who cared for children under 15 years of age, who demonstrated a high prevalence of HBSAg or anti-HBS. Although the prevalence of HBSAg-positive subjects was 4- to 8-fold lower in HCP than in residents, the degree of seroconversion in susceptible seronegative HCP and residents was strikingly similar. These observations suggest that HCP working in a closed institutional setting are at considerable risk of contacting hepatitis B infection.
在1.5年的时间里,对一家智障机构的医护人员(HCP)进行了连续检测,以确定其是否存在乙肝表面抗原(HBSAg)和抗体。1.8%的医护人员存在HBSAg,20.8%的医护人员存在抗-HBS。医护人员血清学阳性的患病率似乎与年龄以及医护人员所照顾的血清学阳性居民的患病率有关。照顾15岁以下儿童的医护人员血清学阳性的发生率更高,这些儿童的HBSAg或抗-HBS患病率较高。虽然HCP中HBSAg阳性受试者的患病率比居民低4至8倍,但易感血清学阴性的医护人员和居民的血清转化率却惊人地相似。这些观察结果表明,在封闭机构环境中工作的医护人员面临感染乙肝的相当大风险。