Mu G F
Department of Microbiology and Immunology, Faculty of Basic Medicine, Peking Union Medical College, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1992 May;26(3):174-5.
An epidemic of Acute Hemorrhagic Conjunctivitis (AHC) broke out in Shanghai, Henan and Fujian provinces of China in 1986. Twenty four strains of etiologically suspected virus were then isolated but not correctly identified. In 1990 9 out of 24 strains from these three places were re-examined by us in our laboratory, and found feasible to be neutralized by CA 24V antiserum, but not by antiserum to EV 70 as once reported by Henan. It was also found that these viruses (one strain from each of these three places) produced pathogenic changes in suckling mice, showed definite immuno-fluorescence with Mcabs, and were neutralized by McAbs against CA 24V which was isolated from Beijing by our laboratory in 1988. It is evident that all the isolates isolated from Shanghai, Henan and Fujian provinces in 1986 were Coxsackie-virus A 24 variant (CA 24V).
1986年，中国上海、河南和福建省爆发了急性出血性结膜炎（AHC）疫情。当时分离出了24株病因疑似病毒，但未得到正确鉴定。1990年，我们实验室对来自这三个地方的24株病毒中的9株进行了重新检测，发现它们可被CA 24V抗血清中和，但不像河南曾报道的那样可被EV 70抗血清中和。还发现这些病毒（来自这三个地方各一株）在乳鼠中产生致病变化，与单克隆抗体呈现明确的免疫荧光反应，并被我们实验室1988年从北京分离的针对CA 24V的单克隆抗体所中和。显然，1986年从上海、河南和福建省分离出的所有毒株均为柯萨奇病毒A 24变异株（CA 24V）。
