Mu G F
Department of Microbiology and Immunology, Faculty of Basic Medical Sciences, Peking Union Medical College, Beijing.
Zhonghua Yu Fang Yi Xue Za Zhi. 1990 May;24(3):129-31.
An epidemic of acute hemorrhagic conjunctivitis (AHC) occurred in Beijing during August-September in 1988. Conjunctival swabs were collected from 50 AHC patients at the Eye Clinic of the Peking Union Medical College Hospital. 25 strains of viruses were isolated with Hela cell cultures. All the viral isolates were identified as Coxsackievirus A 24 variant (CA 24 v) with antiserum from the Center for Disease Control, U. S. A. Paired serum samples from 30 AHC patients were examined for neutralizing against a representative strain of the viral isolates. 24 of them (80%) showed a fourfold or greater rise in neutralizing antibody titers. The results indicate that CA 24 v was the etiologic agent responsible for the 1988 epidemic of AHC. This is the first time an epidemic of AHC caused by CA 24 v is reported in the mainland of China.
1988年8月至9月间，北京发生了急性出血性结膜炎（AHC）疫情。在北京协和医院眼科门诊，从50例AHC患者中采集了结膜拭子。用Hela细胞培养分离出25株病毒。用美国疾病控制中心的抗血清将所有病毒分离株鉴定为柯萨奇病毒A24变种（CA 24 v）。检测了30例AHC患者的双份血清样本对一种具有代表性的病毒分离株的中和作用。其中24例（80%）的中和抗体滴度有四倍或更高的升高。结果表明，CA 24 v是1988年AHC疫情的病原体。这是中国大陆首次报道由CA 24 v引起的AHC疫情。
