PALADE G E
J Biophys Biochem Cytol. 1955 Nov 25;1(6):567-82. doi: 10.1083/jcb.1.6.567.
A survey of a large number of different cell types has indicated the presence of a network of membrane-bound cavities (the endoplasmic reticulum) in the cytoplasm of all cell types examined, with the exception of the mature erythrocyte. In its simplest form, encountered in seminal epithelia and in leucocytes, the reticulum consists mainly of interconnected strings of vesicles and appears to be randomly disposed in three dimensions. Local differentiations occur within the endoplasmic reticulum of all the cell types studied. The membrane limiting the cavities of the endoplasmic reticulum appears to be continuous with the cell membrane and the nuclear membranes.
对大量不同细胞类型的调查表明,在除成熟红细胞外的所有被检查细胞类型的细胞质中,都存在一个由膜结合腔组成的网络(内质网)。在精子上皮细胞和白细胞中发现的最简单形式的内质网,主要由相互连接的囊泡串组成,并且似乎在三维空间中随机分布。在所研究的所有细胞类型的内质网内都存在局部分化。限制内质网腔的膜似乎与细胞膜和核膜是连续的。