PALADE G E
J Biophys Biochem Cytol. 1955 Jan;1(1):59-68. doi: 10.1083/jcb.1.1.59.
A particulate component of small dimensions (100 to 150 A) and high density is described in the ground substance of the cytoplasm of mammalian and avian cells. In many cell types that seem to have in common a high degree of differentiation, the new component is preferentially associated with the membrane of the endoplasmic reticulum; whereas in other cell types, characterized by rapid proliferation, it occurs more or less freely distributed in the ground substance of the cytoplasm. In the Discussion an attempt is made to integrate the observations presented in this paper with the already available cytological, histochemical, and cytochemical information.
在哺乳动物和鸟类细胞的细胞质基质中,描述了一种尺寸小(100至150埃)且密度高的颗粒成分。在许多似乎具有高度分化共性的细胞类型中,这种新成分优先与内质网的膜相关联;而在其他以快速增殖为特征的细胞类型中,它或多或少自由地分布在细胞质基质中。在讨论部分,试图将本文所呈现的观察结果与已有的细胞学、组织化学和细胞化学信息整合起来。