Kopytova F V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1992 Mar-Apr;42(2):341-50.
Spectral analysis (ACG and gSP) of the impulse activity of the neurones of the old rabbits sensorimotor cortex allowed to reveal a trace recruitment of the rhythm--CR analogue to time--in after-action f rhythmic stimulation. Connection was established between the number of presented series of periodic electrocutaneous stimulation and expressiveness of the trace rhythm recruitment depending on the animals age. Trace rhythm recruitment took place slower in old animals (54-56 months) than in young ones (up to 1 year), chiefly in 2-3 experimental days after 2-4 series of rhythmic stimulation and was preserved in a small percent of cases the next day after stimulation. In the background activity of a number of neurones an initial periodicity was discovered, which was intensified under the influence of stimulation by another frequency, or the initial rhythm was extinguished, and stimulation rhythm was reproduced. Periodical stimulation in very old animals (66-85 months) practically did not evoke plastic reconstructions of the cortical neurones. Under the influence of the stimulation a non-specific trace increase of the frequency of neurones background activity of the old animals was observed. The revealed characteristics of plastic neurones properties may testify to projected disturbances of mnestic processes at definite age stages of normal aging.
对老年兔感觉运动皮层神经元冲动活动进行频谱分析（ACG和gSP），发现在节律性刺激后的动作电位中存在一种类似时间的节律——CR的微量募集。根据动物年龄，确定了周期性电皮肤刺激的呈现次数与微量节律募集的明显程度之间的联系。老年动物（54 - 56个月）的微量节律募集比幼年动物（1岁以下）发生得慢，主要在2 - 4次节律性刺激后的2 - 3个实验日内出现，且在刺激后第二天仅有一小部分情况保留。在一些神经元的背景活动中发现了初始周期性，在另一种频率刺激的影响下，这种周期性增强，或者初始节律消失，刺激节律重现。在非常老龄的动物（66 - 85个月）中，周期性刺激几乎不会引起皮层神经元的可塑性重构。在刺激影响下，观察到老年动物神经元背景活动频率有非特异性的微量增加。所揭示的神经元可塑性特性可能证明在正常衰老的特定年龄阶段记忆过程存在预期的紊乱。
