Lichtman M A
Nouv Rev Fr Hematol. 1975 Nov-Dec;15(6):625-32.
The precise changes in adenosine triphosphate (ATP) during red cell aging have not been established. Studies of ATP content based on cell density, a presumptive index of red cell age, observations in anemic subjects in whom age-dependent hemeolysis may occur and studies of the loss of metabolic capability with aging, suggest that the reduction in red cell ATP may be a continuous process, approximating a negative expotential function. Several experimental approaches could be used to support or refute this hypothesis.
红细胞衰老过程中三磷酸腺苷（ATP）的确切变化尚未明确。基于细胞密度（红细胞年龄的一个推测指标）对ATP含量的研究、对可能发生年龄依赖性溶血的贫血患者的观察以及对衰老过程中代谢能力丧失的研究表明，红细胞ATP的减少可能是一个持续的过程，近似于负指数函数。可以采用几种实验方法来支持或反驳这一假设。
