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[人红细胞变形性的ATP依赖性和非ATP依赖性变化]

[ATP-dependent and ATP-independent changes in deformability of human erythrocytes].

作者信息

Tannert C, Steinhoff A, Rapoport I, Elsner R, Rapoport S M

出版信息

Acta Biol Med Ger. 1980;39(2-3):199-205.

PMID:7424340
Abstract

By means of a simple filtration procedure it is shown that the deformability of red blood cells depends indirectly on their relative ATP-concentration. Losses in deformability were observed even with concentrations of ATP, which occur in the course of normal ageing of red blood cells in situ. If erythrocytes are incubated for longer times, their membrane is alterated to such a degree, that the changes cannot be reversed solely by restitution of ATP. The cells remain rigid.

摘要

通过一种简单的过滤程序表明,红细胞的可变形性间接取决于其相对ATP浓度。即使在原位红细胞正常老化过程中出现的ATP浓度下,也观察到了可变形性的损失。如果将红细胞孵育更长时间,其膜会发生改变,以至于仅通过恢复ATP无法逆转这些变化。细胞保持僵硬。

相似文献

1
[ATP-dependent and ATP-independent changes in deformability of human erythrocytes].[人红细胞变形性的ATP依赖性和非ATP依赖性变化]
Acta Biol Med Ger. 1980;39(2-3):199-205.
2
[Studies of the deformability of preserved red blood cells using a simple filtration method].
Acta Biol Med Ger. 1979;38(11-12):1595-600.
3
Rejuvenation of aged erythrocytes by incorporating phosphoenolpyruvate into the cells.通过将磷酸烯醇丙酮酸掺入细胞中来使衰老红细胞恢复活力。
Acta Biol Med Ger. 1981;40(4-5):691-7.
4
Does ATP decrease exponentially during red cell aging?红细胞衰老过程中ATP含量是否呈指数下降?
Nouv Rev Fr Hematol. 1975 Nov-Dec;15(6):625-32.
5
31P NMR studies on rejuvenation of outdated red blood cells: complete regeneration of ATP is accompanied by partial Mg-ATP recomplexation.31P核磁共振研究过期红细胞的复苏:ATP的完全再生伴随着Mg-ATP的部分重新复合。
Haematologia (Budap). 1989;22(2):79-87.
6
Factors that limit whole cell deformability in erythrocytes after calcium loading and ATP depletion.钙加载和ATP耗竭后限制红细胞全细胞变形性的因素。
Prog Clin Biol Res. 1981;55:423-37.
7
[Erythrocyte deformability and adenosine triphosphate (ATP) levels in normal pregnancy and puerperium].[正常妊娠和产褥期的红细胞变形性及三磷酸腺苷(ATP)水平]
Nihon Sanka Fujinka Gakkai Zasshi. 1984 Nov;36(11):2079-84.
8
Reduced red cell deformability associated with blood flow and platelet activation: improved by dipyridamole alone or combined with aspirin.与血流和血小板活化相关的红细胞变形性降低:单独使用双嘧达莫或与阿司匹林联合使用可改善。
Cardiovasc Res. 1995 Nov;30(5):725-30.
9
[Drugs acting on erythrocytes].[作用于红细胞的药物]
Ric Clin Lab. 1983;13 Suppl 3:257-62.
10
Erythrocyte deformability in a red cell ageing model.
Ric Clin Lab. 1978 Jan-Jun;8(1-2):65-71.

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Ca2+-Mg2+-ATPase activity of human red blood cells in healthy and diabetic volunteers.健康和糖尿病志愿者体内人类红细胞的钙镁ATP酶活性
Klin Wochenschr. 1987 Jan 5;65(1):17-21. doi: 10.1007/BF01785521.