Levitz M, Raju U, Katz J, Finlay T H, Brind J L, Arcuri F, Castagnetta L
Department of Obstetrics and Gynecology, New York University Medical Center, New York 10016.
Steroids. 1992 Oct;57(10):485-7. doi: 10.1016/0039-128x(92)90042-8.
Human breast cyst fluid (BCF) contains an esterase that on the basis of electrophoretic mobility and response to inhibitors differs from those found in the plasma. From a total of 384 BCF samples analyzed for esterase using p-nitrophenyl hexanoate as substrate, 149 (39%) showed significant activity. The samples had been analyzed for the concentrations of the sulfates of estrone, estriol, dehydroepiandrosterone, as well as the potassium and sodium cations (K+/Na+). The data were submitted to statistical analysis using the Spearman rank order test. The esterase-positive samples exhibited a significant positive association with each of the steroid sulfates and the K+/Na+ ratios. Except for protein concentration, there was no significant correlation between the esterase-positive and esterase-negative cysts. These observations may have physiological significance in that high K+/Na+ ratio cysts have been related to the histological status of the cyst.
人乳腺囊肿液（BCF）含有一种酯酶，基于电泳迁移率和对抑制剂的反应，它与血浆中的酯酶不同。在总共384份以己酸对硝基苯酯为底物分析酯酶的BCF样本中，149份（39%）显示出显著活性。这些样本已分析了雌酮、雌三醇、脱氢表雄酮的硫酸盐浓度，以及钾和钠阳离子（K⁺/Na⁺）。数据使用Spearman等级顺序检验进行统计分析。酯酶阳性样本与每种甾体硫酸盐和K⁺/Na⁺比值均呈现显著正相关。除蛋白质浓度外，酯酶阳性囊肿和酯酶阴性囊肿之间无显著相关性。这些观察结果可能具有生理意义，因为高K⁺/Na⁺比值囊肿与囊肿的组织学状态有关。
