Holland E J, Mahanti R L, Belongia E A, Mizener M W, Goodman J L, Andres C W, Osterholm M T
Department of Ophthalmology, University of Minnesota Hospital and Clinic, Minneapolis.
Am J Ophthalmol. 1992 Dec 15;114(6):680-4. doi: 10.1016/s0002-9394(14)74044-9.
An epidemic of herpes simplex virus type 1 occurred in 60 of 175 wrestlers (34%) attending a four-week intensive training camp. Five of these 60 patients (8%) developed ocular involvement that included follicular conjunctivitis, blepharitis, and phlyctenular disease. Cultures of the conjunctiva and eyelid vesicles were positive for herpes simplex virus type 1 in four of the five patients with ocular disease. The viral isolates were compared by restriction-endonuclease analysis, which disclosed that three of the four isolates were the same strain. None of the patients had corneal involvement and there has been no evidence of viral recurrence to date. Herpes simplex virus type 1 is a health risk for wrestlers, and ocular infections are part of the clinical spectrum. Prompt diagnosis and appropriate management of the outbreak may reduce the severity of the outbreak transmission.
在参加为期四周强化训练营的175名摔跤运动员中,有60人(34%)发生了1型单纯疱疹病毒疫情。这60名患者中有5人(8%)出现眼部感染,包括滤泡性结膜炎、睑缘炎和泡性疾病。5例眼部疾病患者中有4例结膜和眼睑水疱培养物检测出1型单纯疱疹病毒呈阳性。通过限制性内切酶分析对病毒分离株进行比较,结果显示4株分离株中有3株为同一菌株。所有患者均无角膜受累,迄今为止也没有病毒复发的证据。1型单纯疱疹病毒对摔跤运动员构成健康风险,眼部感染是其临床症状的一部分。对疫情进行及时诊断和适当管理可能会降低疫情传播的严重程度。