[肌肽及其类似物与自由基相互作用的直接测量]
[Direct measurement of the interaction of carnosine and its analogs with free radicals].
作者信息
Boldyrev A A, Kurella E G, Rubtsov A M, Tiulina O V, Shara M, Shentiurts M
机构信息
Josef Stefan Institute, University of Ljubljana, Slovenia.
出版信息
Biokhimiia. 1992 Sep;57(9):1360-5.
An ESR study of interactions of carnosine and its derivatives with free radicals has been carried out. In model systems the spin trap OH. radical adduct generation has been shown to decrease significantly in the presence of carnosine in a pronounced concentration-dependent manner. A comparative study of effects of some other histidine-containing dipeptides on this process has revealed a similarity in anserine, homocarnosine, and acetylcarnosine actions.
已开展了一项关于肌肽及其衍生物与自由基相互作用的电子自旋共振（ESR）研究。在模型系统中，已表明在肌肽存在下，自旋捕获羟基自由基加合物的生成以明显的浓度依赖性方式显著减少。对其他一些含组氨酸的二肽对该过程的影响进行的比较研究揭示了鹅肌肽、高肌肽和乙酰肌肽作用的相似性。
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