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[黑腹果蝇中mod(mdg4)基因新突变的制备与分析]

[Preparation and analysis of new mutations of the mod(mdg4) gene in Drosophila melanogaster].

作者信息

Kozitsina M V, Georgiev P G

出版信息

Genetika. 1992 Oct;28(10):75-82.

PMID:1334898
Abstract

In the previous work, we described the modifier of mdg4 gene and obtained one mutation in the locus designated as mod (mdg4). Here we tried to obtain new alleles of this gene participating in transcription control of mdg4. P-M hybrid dysgenesis and EMS treatment failed to give mutations. On the other hand, one strain containing mod (mdg4) 1u1 mutation spontaneously became unstable. In this strain, four novel mod (mdg4) alleles with different phenotypes have been obtained. The mutation obtained seem to be the regulatory ones.

摘要

在之前的工作中,我们描述了mdg4基因的修饰因子,并在命名为mod(mdg4)的位点获得了一个突变。在此,我们试图获得参与mdg4转录调控的该基因的新等位基因。P-M杂种不育和EMS处理未能产生突变。另一方面,一个含有mod(mdg4)1u1突变的品系自发变得不稳定。在这个品系中,获得了四个具有不同表型的新型mod(mdg4)等位基因。所获得的突变似乎是调控性的。

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