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[巨细胞病毒与妊娠。胎儿及新生儿风险]

[Cytomegalovirus and pregnancy. Fetal and neonatal risk].

作者信息

Gaudy V, Lamy M E, Mulongo N K, Van Lierde M

机构信息

Service d'Obstétrique, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Belgique.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1992;21(7):779-90.

PMID:1334984
Abstract

A review of the literature shows that 36% of pregnant women are not immunized against cytomegalovirus; 2.11% of these patients will have a primary infection during their pregnancy. The fetal transmission rate is 30%. Viruria after delivery is the unique proven sign of infection; but is only present in 4 to 5 infants per 1,000 births. Of those, 17% will be symptomatic at delivery and 10% will develop sequels as late as seven years later. CMV can be reactivated during pregnancy. These cases are less dangerous but the fetal risk is always present.

摘要

文献综述表明,36%的孕妇未接种抗巨细胞病毒疫苗;其中2.11%的患者在孕期会发生原发性感染。胎儿传播率为30%。产后病毒尿是唯一已证实的感染迹象;但每1000例出生中仅4至5例婴儿会出现。其中,17%的婴儿在出生时会出现症状,10%的婴儿会在晚至七岁时出现后遗症。巨细胞病毒在孕期可被重新激活。这些情况危险性较小,但胎儿风险始终存在。

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