大鼠肝脏富含溶酶体组分的电子显微镜观察。
Electron microscopy of lysosomerich fractions from rat liver.
作者信息
NOVIKOFF A B, BEAUFAY H, DE DUVE C
出版信息
J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):179-84.
Abstract
A preliminary electron microscope study has revealed the presence in lysosome-rich fractions, isolated from rat liver, of hitherto undescribed cytoplasmic particles, called "dense bodies." Approximately 0.37 micro in length, the dense bodies often possess an internal cavity and external membrane. They contain many electron-dense granules 55 to 77 A, or less, in diameter. Such dense bodies are also visible in electron micrographs of parenchymatous cells in liver sections. The correlations between dense bodies and lysosomes are listed, but until pure preparations are available it is not possible to assert that dense bodies and lysosomes are identical.
摘要
一项初步的电子显微镜研究显示，从大鼠肝脏分离出的富含溶酶体的组分中存在迄今未描述过的细胞质颗粒，称为“致密体”。致密体长度约为0.37微米，通常具有内部腔室和外部膜。它们含有许多直径为55至77埃或更小的电子致密颗粒。在肝脏切片实质细胞的电子显微照片中也可见到这种致密体。文中列出了致密体与溶酶体之间的相关性，但在获得纯制剂之前，无法断言致密体与溶酶体是相同的。
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