Avakian R M
Biull Eksp Biol Med. 1976 Jul;82(7):789-92.
The effect of 5-oxytryptophane (5-OT) and of parachlor-phenylalanine (pCPA) on the behaviouristic EEG manifestations of metrazol convulsions in electrostimulation and destruction of the striatum was studied. The effect of the preparations on the myoclonia and the spike-wave rhythm caused by metrazol did not largely depend on the functional condition of the corpus striatum. The capacity of 5-OT to facilitate, and of pCPA to aggravate the course of generalized convulsions and of the postconvulsive state became enhanced in stimulation and was eliminated after the destruction of the striatum.
研究了5-羟色氨酸（5-OT）和对氯苯丙氨酸（pCPA）对电刺激和损毁纹状体时戊四氮惊厥行为性脑电图表现的影响。这些制剂对戊四氮引起的肌阵挛和棘波节律的影响在很大程度上不依赖于纹状体的功能状态。在刺激时，5-OT促进和pCPA加重全身性惊厥及惊厥后状态的能力增强，而在损毁纹状体后这种能力消失。
