Moreno-Fierros L, Campos-Rodríguez R, Enríquez-Rincón F
Department of Cell Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México, DF.
Arch Med Res. 1992;23(2):165-8.
The kinetics of the anti-amebic antibody producing cell (APC) response was analyzed by a spot forming cell (SFC) assay, after a single dose of glutaraldehyde fixed amebas (GFA) by intragastric, rectal and intraperitoneal routes. It was found that mice elicited both local and systemic immune responses in Peyer's patches and spleen, by either local or systemic stimulation. The analysis of the isotype of the anti-amebic APC in mice given four times the GFA by the mentioned routes revealed that mice produced anti-amebic APC of the three major isotypes in both spleen and Peyer's patches.
