Micouin L, Chinain M, Asin P, Legrand A M
Institut Territorial de Recherches Médicales Louis Malardé, Papeete, Tahiti, French Polynesia.
Bull Soc Pathol Exot. 1992;85(5 Pt 2):474-7.
Seven clonal strains of Gambierdiscus toxicus isolated from three ciguateric areas around Tahiti island were mass cultured and extracted for ciguatoxins and maitotoxin. CTX analogs were detected only in one clone (GTP1), suggesting that CTX production may be strain-dependent. However, this in vitro production of CTXs, which remains fairly poor with regards to the toxicity levels encountered in wild G. toxicus, is not a stable temporal characteristic. On the other hand, maitotoxic compounds were detected in all 7 strains in copious amount, especially in clone GTH2.
从塔希提岛周围三个雪卡毒素中毒地区分离出的7株甘比尔藻毒素克隆菌株进行了大规模培养，并提取了雪卡毒素和刺尾鱼毒素。仅在一个克隆株（GTP1）中检测到CTX类似物，这表明CTX的产生可能具有菌株依赖性。然而，CTX在体外的产生，相对于野生有毒甘比尔藻中遇到的毒性水平仍然相当低，且不是一个稳定的时间特征。另一方面，在所有7个菌株中都大量检测到了刺尾鱼毒素化合物，尤其是在克隆株GTH2中。
