Quijada C, Galleguillos F
Clínica Servet, Santiago de Chile.
Rev Med Chil. 1992 Feb;120(2):142-6.
In a double blind study, 20 patients who presented with acute episodes of asthma were randomized to treatment with nebulized salbutamol (5 mg) of subcutaneous salbutamol (0.5 mg). The clinical conditions were not significantly different before or after treatment in both groups. Significant bronchial dilation was obtained to a similar level in both groups. The heart rate increased significantly in the group treated by subcutaneous injection. Other side effects were minor and similar in both groups. Thus nebulized salbutamol may be used to treat acute asthma in selected patients.
在一项双盲研究中，20名出现哮喘急性发作的患者被随机分为接受雾化沙丁胺醇（5毫克）治疗组和皮下注射沙丁胺醇（0.5毫克）治疗组。两组治疗前后的临床状况无显著差异。两组均获得了相似程度的显著支气管扩张。皮下注射治疗组的心率显著增加。两组的其他副作用均较轻微且相似。因此，雾化沙丁胺醇可用于治疗部分选定患者的急性哮喘。
