小鼠t因子：t位点等位基因与H-2位点等位基因之间的关联。
Murine t factors: an association between alleles at t and at H-2.
作者信息
Levinson J R, McDevitt H O
出版信息
J Exp Med. 1976 Sep 1;144(3):834-9. doi: 10.1084/jem.144.3.834.
Abstract
Lymphocytes from tx-mutant mice have a definite and consistent pattern of reactivity in MLR. Cells from t-mutant mice within a complementation group usually fail to stimulate each other, while cells from mutants in different complementation groups stimulate each other strongly. This indicates that tx-mutant types are associated with certain H-2 haplotypes, and that members of any give complementation group share the same H-2 haplotype.
摘要
来自 tx 突变小鼠的淋巴细胞在混合淋巴细胞反应中有明确且一致的反应模式。同一互补组内 t 突变小鼠的细胞通常不能相互刺激，而来自不同互补组的突变体的细胞则能强烈地相互刺激。这表明 tx 突变类型与某些 H-2 单倍型相关，并且任何给定互补组的成员共享相同的 H-2 单倍型。
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