居住在巴西亚马逊地区的两个不同种族群体中人类嗜T淋巴细胞病毒I型抗体的流行情况。

Prevalence of HTLV-I antibody among two distinct ethnic groups inhabiting the Amazon region of Brazil.

作者信息

Nakauchi C M, Maruyama K, Kanzaki L I, Linhares A C, Azevedo V N, Fukushima T, Miyauchi M, Koshikawa N, Tamayama C, Mochizuki S

机构信息

Instituto Evandro Chagas, Fundação Nacional de Saúde, Belém, Pará, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1992 Jul-Aug;34(4):323-8. doi: 10.1590/s0036-46651992000400009.

DOI:10.1590/s0036-46651992000400009

PMID:1342089

Abstract

HTLV-I seroprevalences of 3.63% (02/55), 12.19% (10/82) and 13.88% (10/72) were demonstrated among Tiryio, Mekranoiti and Xicrin Amazonian Indians, respectively, by the Western blotting enzyme assay (WBEI). By indirect immunoelectron microscopy (IIEM), 2 Tiriyo, 9 Mekranoiti and 6 Xicrin Amerindians were reactive. Of 44 serum samples from Japanese immigrants, none reacted by any of the techniques before mentioned. One, 8 and 6 serum samples from Tiryio, Mekranoiti and Xicrin Indians, respectively, were both WBEI and IIEM positive. Our results strongly suggest that HTLV-I and/or an HTLV-I antigenic variant circulate (s) among populations living in the Amazon region of Brazil.

摘要

通过蛋白质印迹酶分析法（WBEI），在蒂里约、梅克拉诺伊蒂和希克林亚马逊印第安人中，HTLV-I血清阳性率分别为3.63%（2/55）、12.19%（10/82）和13.88%（10/72）。通过间接免疫电子显微镜检查（IIEM），2名蒂里约人、9名梅克拉诺伊蒂人和6名希克林美洲印第安人呈阳性反应。在44份日本移民的血清样本中，没有一份通过上述任何技术检测呈阳性。分别来自蒂里约、梅克拉诺伊蒂和希克林印第安人的1份、8份和6份血清样本，蛋白质印迹酶分析法和间接免疫电子显微镜检查均呈阳性。我们的结果有力地表明，HTLV-I和/或HTLV-I抗原变体在生活在巴西亚马逊地区的人群中传播。