Bava A J, Negroni R
Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Rev Inst Med Trop Sao Paulo. 1992 Jul-Aug;34(4):335-40.
Some epidemiological characteristics of 105 cases of cryptococcosis diagnosed in Argentina, between 1981-1990, were studied. Until 1987, the annual number of cases was 4-8. It has increased since 1988 by AIDS influence and reached 35 cases in 1990. The annual number of cases non associated with AIDS has remained in 3-7 cases. The age median of the all patients, AIDS and non AIDS associated cases was 30, 30 and 45 years old, respectively. The 20-39 years old group was the most affected and the age distribution was different in AIDS and non AIDS population. Masculine predominance was more evident in AIDS than in non AIDS associated cases. The predisposing factor was AIDS in 57 patients, another different factor in 20 and unknown in 28 cases. The indirect estimation of the percentage of AIDS cases with cryptococcosis was > or = 6.19% (57 cases in 920 HIV+) during 1981-1990 this period. Cryptococcus neoformans variety neoformans was isolated from 101 cases and the gattii variety (serotype B) from only 4. The obtained data are similar to those observed in Europe and United States.
对1981年至1990年间在阿根廷诊断出的105例隐球菌病病例的一些流行病学特征进行了研究。直到1987年,病例年数为4至8例。自1988年以来,受艾滋病影响病例数增加,1990年达到35例。与艾滋病无关的病例年数保持在3至7例。所有患者、艾滋病相关病例和非艾滋病相关病例的年龄中位数分别为30岁、30岁和45岁。20至39岁年龄组受影响最大,艾滋病患者和非艾滋病患者的年龄分布不同。男性优势在艾滋病患者中比在非艾滋病相关病例中更明显。57例患者的诱发因素是艾滋病,20例为其他不同因素,28例不明。1981年至1990年期间,隐球菌病艾滋病病例百分比的间接估计值≥6.19%(920例HIV+患者中有57例)。从101例中分离出新型隐球菌新型变种,仅4例分离出加蒂变种(血清型B)。获得的数据与在欧洲和美国观察到的数据相似。