血清胆固醇——年轻及年长黑人和白人冠心病死亡率的危险因素。查尔斯顿心脏研究，1960 - 1988年。
Serum cholesterol--risk factor for coronary disease mortality in younger and older blacks and whites. The Charleston Heart Study, 1960-1988.
作者信息
Keil J E, Sutherland S E, Knapp R G, Gazes P C
机构信息
Department of Biostatistics, Epidemiology and Systems Science, Medical University of South Carolina, Charleston 29425.
出版信息
Ann Epidemiol. 1992 Jan-Mar;2(1-2):93-9.
Serum total cholesterol (> or = 6.7 mmol/L) measured in 1960 in the Charleston Heart Study cohort was found to be a risk for mortality from coronary heart disease during the period of 1960 to 1988 in white men (relative risk [RR] 1.5; 95% confidence interval [CI]: 1.1, 2.2), white women (RR 1.7; 95% CI: 1.1, 2.7), and black women (RR 1.6; 95% CI: .9, 2.9) after age, systolic blood pressure, smoking status, education level, obesity, and diabetes were considered. For black men, the relative risk was .96 (95% CI, .39, 2.39). Only among white women was the relative risk (RR 2.4; 95% CI, 1.2, 4.5) increased among those in the older ages (55 to 74) in 1960. The evidence for cholesterol as a risk factor for coronary disease mortality in black men is inconclusive and requires further study.
在查尔斯顿心脏研究队列中，1960年测得血清总胆固醇（≥6.7毫摩尔/升）是1960年至1988年期间白人男性（相对风险[RR]1.5；95%置信区间[CI]：1.1，2.2）、白人女性（RR 1.7；95% CI：1.1，2.7）和黑人女性（RR 1.6；95% CI：0.9，2.9）冠心病死亡的一个风险因素，这些是在考虑了年龄、收缩压、吸烟状况、教育水平、肥胖和糖尿病之后得出的结果。对于黑人男性，相对风险为0.96（95% CI，0.39，2.39）。仅在白人女性中，1960年年龄较大（55至74岁）的人群相对风险（RR 2.4；95% CI，1.2，4.5）有所增加。胆固醇作为黑人男性冠心病死亡风险因素的证据尚无定论，需要进一步研究。
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