Bistriceanu G
Serviciul de fiziopatologie respiratorie, Institutul de pneumoftiziologie M. Nasta, Bucureşti.
Pneumoftiziologia. 1992 Apr-Sep;41(2-3):153-7.
The diagnosis of distal obstructive syndrome (DOS) is based on the test of lung ventilation function. The tests applied (FEF25-75, MEF50, MEF25) are more sensible than in the routine spirography exploration (FEV1, FEV1.0 x 100/VC), because they evaluate the efficiency of ventilation in those conditions in which the force of the respiratory muscles plays a secondary part and, therefore, cannot hide a flow decrease caused by the obstruction of small pathways (less than 2 mm in diameter). FEF25-75 is measured on the same forced maximum expirogram as FEV1.0. MEF50 and MEF25 are parameters derived from the flow-volume curve. The introduction of these tests into the routine exploration of pulmonary ventilation will improve considerably the diagnosis of early COPD forms.
远端阻塞综合征（DOS）的诊断基于肺通气功能测试。所应用的测试（FEF25-75、MEF50、MEF25）比常规肺量计检查（FEV1、FEV1.0×100/VC）更灵敏，因为它们评估的是在呼吸肌力量起次要作用的情况下的通气效率，因此不会掩盖由小气道（直径小于2毫米）阻塞引起的气流减少。FEF25-75与FEV1.0在同一次最大用力呼气图上测量。MEF50和MEF25是从流量-容积曲线得出的参数。将这些测试引入肺通气的常规检查中将大大改善早期慢性阻塞性肺疾病（COPD）的诊断。
