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[低强度激光辐射对大鼠皮肤伤口愈合的形态功能特征]

[The morphofunctional characteristics of the healing of a skin wound in rats by exposure to low-intensity laser radiation].

作者信息

Petrova M B

出版信息

Morfologiia. 1992 Jun;102(6):112-21.

PMID:1343249
Abstract

A specific course of the reparative process in the skin under the influence of low-energy laser radiation was studied in albino rats by a complex of methods. High phagocytic activity of macrophages was observed as early as 6 h after trauma. It resulted in rapid debridement of the wound and prepared conditions for the proliferation phase. At later terms (5 and 10 days) the reaction to laser irradiation manifested itself as a powerful vascularization of the wound and increased amount of secreting fibroblasts. Favorable conditions for the reparative process resulting from the laser action were responsible for its optimum result as well. Cicatrization of the wound in animals given laser therapy was accompanied by the formation of hair follicles and the structure of the scar approximated to the structure of the intact skin.

摘要

通过一系列方法,对白化大鼠受低能量激光辐射影响下皮肤修复过程的特定进程进行了研究。早在创伤后6小时就观察到巨噬细胞具有高吞噬活性。这导致伤口迅速清创,并为增殖期创造了条件。在后期(5天和10天),对激光照射的反应表现为伤口有力的血管形成和分泌性成纤维细胞数量增加。激光作用所产生的有利于修复过程的条件也是其取得最佳效果的原因。接受激光治疗的动物伤口愈合过程中伴有毛囊形成,瘢痕结构接近正常皮肤结构。

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