Braun R, Lange H, Mangold U, Mangold R
Z Naturforsch C Biosci. 1976 May-Jun;31(5-6):298-303.
N-methyl-N-beta-chloroethylhydrazine and its benzaldehydhydrazone inhibit the influx of [6-3H]-uracil and L-[U-14C]leucin in yeast cells as well as the incorporation in RNA and protein. Experiments with synchronously and asynchronously growing cells showed the N-methyl-N-beta-chloroethylhydrazine essentially influences the dividing phase while the benzaldehydhydrazone is more effective in the growth phase. The effect of these two substances on respiration, glycolysis and the concentration of fructose-1,6-diphosphate, triose phosphate, and adenosine triphosphate is small.
N-甲基-N-β-氯乙基肼及其苯甲醛腙可抑制[6-³H]尿嘧啶和L-[U-¹⁴C]亮氨酸流入酵母细胞，以及它们掺入RNA和蛋白质的过程。对同步生长和异步生长细胞进行的实验表明，N-甲基-N-β-氯乙基肼主要影响分裂期，而苯甲醛腙在生长期更有效。这两种物质对呼吸作用、糖酵解以及果糖-1,6-二磷酸、磷酸丙糖和三磷酸腺苷浓度的影响较小。
