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盐酸N-甲基-N-β-氯乙基肼对酵母细胞(酿酒酵母)生长和繁殖的影响(作者译)

[Effect of N-methyl-N-beta-chloroethyl-hydrazine-HCl on the growth and multiplication of yeast cells (Saccharomyces cerevisiae) (author's transl)].

作者信息

Braun R, Lange H

出版信息

Z Naturforsch C Biosci. 1976 May-Jun;31(5-6):292-7.

PMID:134572
Abstract

N-Methyl-N-beta-chloroethyl-hydrazine-HCl and its benzaldehydhydrazone inhibit growth and multiplication of yeast cells. The DNA-synthesis is partially blocked. After removal of the substances the rate of this synthesis is much more increased than that of RNA and protein. The both substances we tested are more effective than simple alkylhydrazines.

摘要

盐酸N-甲基-N-β-氯乙基肼及其苯甲醛腙可抑制酵母细胞的生长和繁殖。DNA合成被部分阻断。去除这些物质后,这种合成的速率比RNA和蛋白质的合成速率增加得更多。我们测试的这两种物质比简单的烷基肼更有效。

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[On the cytostatic mechanism of action of N-methyl-N-beta-chloroethylhydrazine and its benzaldehydhydrazone (author's transl)].
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