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Effects of danazol on coagulant activity in the rat.

作者信息

Lox C D, Heine M W, DeLeon F, Prein S

机构信息

Department of Obstetrics and Gynecology, Texas Tech Health Sciences Center, Lubbock.

出版信息

Int J Fertil. 1992 Jan-Feb;37(1):48-52.

PMID:1348736
Abstract

Coagulation factor activity was evaluated in female rats treated with danazol. Following 30 days of treatment, slight decreases in factor VII and X activities were noted. After 60 days, a prolongation of the prothrombin time, as well as a decrease in factor VII, was noted. The data suggest that in the rodent, danazol has minimal effects on coagulation activity.

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