上海汉族人群中HLA-DP分布——聚合酶链反应-限制性片段长度多态性研究

HLA-DP distribution in Shanghai Chinese--a study by polymerase chain reaction--restriction fragment length polymorphism.

作者信息

Wang F Q, al-Daccak R, Ju L Y, Lethielleux P, Charron D, Loiseau P, Colombani J

机构信息

Immunogenetics Laboratory, Shanghai Institute of Immunology, Shanghai Second Medical University, People's Republic of China.

出版信息

Hum Immunol. 1992 Feb;33(2):129-32. doi: 10.1016/0198-8859(92)90063-s.

DOI:10.1016/0198-8859(92)90063-s

PMID:1348742

Abstract

One hundred and four normal unrelated Chinese were typed for HLA-DPA1 and DPB1 alleles by polymerase chain reaction-restriction fragment length polymorphism. Increased frequencies of HLA-DPA10201 and DPB10501 were found in this Chinese population as compared with those detected in Caucasoids and blacks.

摘要

采用聚合酶链反应-限制性片段长度多态性方法，对104名无亲缘关系的正常中国人进行了HLA-DPA1和DPB1等位基因分型。与白种人和黑人相比，该中国人群中HLA-DPA10201和DPB10501的频率有所增加。