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上海汉族人群中HLA-DP分布——聚合酶链反应-限制性片段长度多态性研究

HLA-DP distribution in Shanghai Chinese--a study by polymerase chain reaction--restriction fragment length polymorphism.

作者信息

Wang F Q, al-Daccak R, Ju L Y, Lethielleux P, Charron D, Loiseau P, Colombani J

机构信息

Immunogenetics Laboratory, Shanghai Institute of Immunology, Shanghai Second Medical University, People's Republic of China.

出版信息

Hum Immunol. 1992 Feb;33(2):129-32. doi: 10.1016/0198-8859(92)90063-s.

DOI:10.1016/0198-8859(92)90063-s
PMID:1348742
Abstract

One hundred and four normal unrelated Chinese were typed for HLA-DPA1 and DPB1 alleles by polymerase chain reaction-restriction fragment length polymorphism. Increased frequencies of HLA-DPA10201 and DPB10501 were found in this Chinese population as compared with those detected in Caucasoids and blacks.

摘要

采用聚合酶链反应-限制性片段长度多态性方法,对104名无亲缘关系的正常中国人进行了HLA-DPA1和DPB1等位基因分型。与白种人和黑人相比,该中国人群中HLA-DPA10201和DPB10501的频率有所增加。

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HLA-DP distribution in Shanghai Chinese--a study by polymerase chain reaction--restriction fragment length polymorphism.上海汉族人群中HLA-DP分布——聚合酶链反应-限制性片段长度多态性研究
Hum Immunol. 1992 Feb;33(2):129-32. doi: 10.1016/0198-8859(92)90063-s.
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HLA-DPB1 allele mismatches between unrelated HLA-A,B,C,DR (generic) DQA1-identical unrelated individuals with unreactive MLC.在无关的HLA - A、B、C、DR(通用型)、DQA1相同且混合淋巴细胞培养无反应性的无关个体之间的HLA - DPB1等位基因错配。
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Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies.
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