胱胺和高胱胺被哺乳动物酶氧化。
The oxidation of cystamine and homocystamine by mammalian enzymes.
作者信息
BERGERET B, BLASCHKO H
出版信息
Br J Pharmacol Chemother. 1957 Dec;12(4):513-6. doi: 10.1111/j.1476-5381.1957.tb00174.x.
The oxidative deamination of cystamine and homocystamine by mammalian oxidases has been studied. The histaminase of pig kidney oxidizes homocystamine much more slowly than cystamine. The amine oxidase of mammalian liver (guinea-pig, rabbit) oxidizes homocystamine more rapidly than cystamine. Both amines are oxidized by plasma (or serum) of ruminants (ox, sheep, goat) and of the horse. In the enzymatic oxidation of homocystamine both aminogroups are removed; there is no evidence that a ring compound analogous to cystaldimine is accumulating.
已经对哺乳动物氧化酶对胱胺和高胱胺的氧化脱氨作用进行了研究。猪肾的组胺酶氧化高胱胺的速度比氧化胱胺的速度慢得多。哺乳动物肝脏（豚鼠、兔子）的胺氧化酶氧化高胱胺的速度比氧化胱胺的速度快。这两种胺都能被反刍动物（牛、绵羊、山羊）和马的血浆（或血清）氧化。在高胱胺的酶促氧化过程中，两个氨基都被去除；没有证据表明类似于胱硫醚亚胺的环状化合物正在积累。
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