Biophysical studies of recognition sequences for targeting and folding.

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作者信息

Gierasch L M, Jones J D, Landry S J, Stradley S J

机构信息

Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas 75235-9041.

出版信息

Antonie Van Leeuwenhoek. 1992 Feb;61(2):93-9. doi: 10.1007/BF00580613.

DOI:10.1007/BF00580613

PMID:1349802

Abstract

摘要

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Biophysical studies of recognition sequences for targeting and folding.

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本文引用的文献

Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfoleded state depends on two chaperonin proteins and Mg-ATP.从无折叠状态重构活性二聚体核酮糖二磷酸羧化酶依赖于两种伴侣蛋白和Mg-ATP。

Nature. 1989;342(6252):884-9. doi: 10.1038/342884a0.

A simple method for displaying the hydropathic character of a protein.一种展示蛋白质亲水性特征的简单方法。

J Mol Biol. 1982 May 5;157(1):105-32. doi: 10.1016/0022-2836(82)90515-0.

Importance of secondary structure in the signal sequence for protein secretion.蛋白质分泌信号序列中二级结构的重要性。

Proc Natl Acad Sci U S A. 1983 Aug;80(15):4599-603. doi: 10.1073/pnas.80.15.4599.

The differential effect on two hybrid proteins of deletion mutations within the hydrophobic region of the Escherichia coli OmpA signal peptide.大肠杆菌OmpA信号肽疏水区域内缺失突变对两种杂合蛋白的差异影响。

J Biol Chem. 1987 Feb 5;262(4):1716-9.

Kinetic analysis of lamB mutants suggests the signal sequence plays multiple roles in protein export.lamB突变体的动力学分析表明，信号序列在蛋白质输出中发挥多种作用。

J Biol Chem. 1986 Nov 15;261(32):15075-80.

In vivo function and membrane binding properties are correlated for Escherichia coli lamB signal peptides.

Science. 1985 May 31;228(4703):1096-9. doi: 10.1126/science.3158076.

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.特定配体的结合会抑制纯化的前体蛋白导入线粒体。

Nature. 1986;322(6076):228-32. doi: 10.1038/322228a0.

Physiological role during export for the retardation of folding by the leader peptide of maltose-binding protein.麦芽糖结合蛋白前导肽在输出过程中延迟折叠的生理作用。

Proc Natl Acad Sci U S A. 1989 Dec;86(23):9213-7. doi: 10.1073/pnas.86.23.9213.

Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.

J Biol Chem. 1989 Oct 15;264(29):17293-7.

Signal sequences.

Biochemistry. 1989 Feb 7;28(3):923-30. doi: 10.1021/bi00429a001.

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