von Ilberg C, Kleinmann H, Arnold W
Laryngol Rhinol Otol (Stuttg). 1976 May;55(5):420-8.
92 patients suffering from malignant nasopharynx tumors have been examined. They were classified according to their histological diagnosis and compared in point of view clinical particularity and prognosis. The lymphoepithelial carcinoma (LEC) is the most common malignant tumor of this organ. It differs clearly in its clinical behaviour from all other tumors of the nasopharynx. Particularly striking is the early and - apart from rare exeptions - regular involvement of the regional neck lymphnodes. This fact allows an early recognition of the small primary tumor - with its consealed site and poor clinical symptoms - and improves consequently the 3-year-survival-rate of the LEC decisively. By combination of radiological and surgical treatment of the involved neck lymphnodes, the prognosis of the LEC can be further improved. Following our own findings and recent results from the tumor virus research we want to point out that LEC has to be considered as a special disease with its proper etiology and clinical appearance.
对92例鼻咽癌患者进行了检查。根据组织学诊断对他们进行分类，并从临床特点和预后角度进行比较。淋巴上皮癌（LEC）是该器官最常见的恶性肿瘤。其临床行为与鼻咽癌的所有其他肿瘤明显不同。特别显著的是区域颈部淋巴结早期且除罕见例外通常会受累。这一事实使得能够早期识别隐匿部位且临床症状不佳的小原发肿瘤，从而决定性地提高了LEC的3年生存率。通过对受累颈部淋巴结进行放射治疗和手术治疗相结合，LEC的预后可进一步改善。根据我们自己的研究结果以及肿瘤病毒研究的最新成果，我们想指出，LEC必须被视为一种具有其自身病因和临床表现的特殊疾病。
