Metal redistribution in largemouth bass (Micropterus salmoides) in response to restrainment stress and dietary cadmium: role of metallothionein and other metal-binding proteins.
作者信息
Weber D N, Eisch S, Spieler R E, Petering D H
机构信息
Marine and Freshwater Biomedical Core Center, University of Wisconsin-Milwaukee 53201.
Fish stressed by restrainment displayed elevated serum cortisol, copper and zinc levels; dietary cadmium had no effect. 2. Stress/dietary cadmium increased liver copper levels in a metal pool containing metallothionein and non-metallothionein proteins but decreased intestinal zinc bound as low molecular weight forms. 3. After restrainment, zinc losses occurred in dorsal skeletal muscle, ovary and spleen: copper decreased in intestine and pyloric caecum. 4. Dietary cadmium altered intestinal zinc distribution and raised hepatic Cu-binding protein levels but did not alter plasma zinc, copper or cortisol levels. 5. Alterations in zinc and copper concentrations during stress contrast with mammalian models.
Fish Physiol Biochem. 1994 May;13(1):81-91. doi: 10.1007/BF00004122.
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The yellow catfish, Pelteobagrus fulvidraco (Siluriformes) metallothionein cDNA: molecular cloning and transcript expression level in response to exposure to the heavy metals Cd, Cu, and Zn.
