Parilis I I, Kazanov E Iu, Salikhov R S, Khamidov D Kh
Bioorg Khim. 1992 May;18(5):618-22.
Evolutionary trees of proteins analysed by means of computer comparative methods were reconstructed and the level of the structure and functional relationship was revealed. The distance between the percent amino acid contents was used to classify a group of toxins from the sea anemone Radianthus macrodactylus, which proved to belong to long neurotoxins. The scores were calculated by the pattern recognition method. By the use of the distance values, ten phospholipases A2 were divided into two groups, containing representatives of the most closely related organisms.
通过计算机比较方法分析蛋白质的进化树得以重建,结构与功能关系的水平也得以揭示。利用氨基酸含量百分比之间的距离对来自大指海葵的一组毒素进行分类,结果证明它们属于长神经毒素。分数通过模式识别方法计算得出。利用距离值,将十种磷脂酶A2分为两组,每组包含关系最为密切的生物体的代表。