从断奶仔猪腹泻中分离出的产肠毒素大肠杆菌菌株中不同于K88、K99、F41和987P的定居因子。

Colonization factor different from K88, K99, F41 and 987P in enterotoxigenic Escherichia coli strains isolated from postweaning diarrhoea in pigs.

作者信息

Salajka E, Salajkova Z, Alexa P, Hornich M

机构信息

Veterinary Research Institute, Brno, Czechoslovakia.

出版信息

Vet Microbiol. 1992 Sep;32(2):163-75. doi: 10.1016/0378-1135(92)90103-z.

DOI:10.1016/0378-1135(92)90103-z

PMID:1359692

Abstract

A novel common colonization factor was detected in enterotoxigenic strains of Escherichia coli isolated from intestinal contents of piglets affected with postweaning diarrhoea. This factor was antigenically distinct from the previously described K88, K99, F41, 987P, CFAI, CFAII and Att25 fimbrial antigens. E. coli strains possessing this factor adhered to the pig intestinal brush borders and one strain, used in experimental infection in weanlings, colonized the intestinal epithelium and induced diarrhoea. Examination of 212 toxigenic strains of E. coli isolated from weanlings revealed the presence of the novel common colonization factor in 83 strains, belonging to serogroups O25, O108, O138, O141, O147 and O157. The antigen K88 was detected in 47 strains belonging to serogroups O8, O141, O147 and O149.

摘要

从患有断奶后腹泻的仔猪肠道内容物中分离出的产肠毒素大肠杆菌菌株中检测到一种新型共同定居因子。该因子在抗原性上与先前描述的K88、K99、F41、987P、CFAI、CFAII和Att25菌毛抗原不同。具有该因子的大肠杆菌菌株粘附于猪肠道刷状缘，并且在断奶仔猪的实验性感染中使用的一个菌株定植于肠上皮并引起腹泻。对从断奶仔猪中分离出的212株产毒素大肠杆菌菌株进行检查发现，83株菌株中存在这种新型共同定居因子，这些菌株属于O25、O108、O138、O141、O147和O157血清型。在属于O8、O141、O147和O149血清型的47株菌株中检测到K88抗原。