α-甲基酪氨酸对抗精神病药物诱导的食物强化杠杆按压行为抑制的增强作用。
Potentiation by alpha-methyltyrosine of the suppression of food-reinforced lever-pressing behaviour induced by antipsychotic drugs.
作者信息
Ahlenius S, Engel J
出版信息
Acta Pharmacol Toxicol (Copenh). 1977 Jan;40(1):115-25. doi: 10.1111/j.1600-0773.1977.tb02059.x.
Abstract
The mode of action whereby alpha-methyltyrosine (alpha-MT) potentiates the behavioural effects induced by catecholamine receptor blocking antipsychotic drugs was investigated in rats trained to lever-press for food on a fixed-ratio 40 schedule of reinforcement. It was found that alpha-MT (20 mg/kg intraperitoneally - 4 hrs potentiates the effects induced by pimace, causing an alteration of the neuronal function.
摘要
在按固定比率40强化程序训练以按压杠杆获取食物的大鼠中，研究了α-甲基酪氨酸（α-MT）增强儿茶酚胺受体阻断抗精神病药物诱导的行为效应的作用方式。发现α-MT（腹腔注射20毫克/千克 - 4小时）增强了匹莫齐特诱导的效应，导致神经元功能改变。
Zotero 插件