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Resistance of hippocampal CA-1 noradrenergic fibers to five minutes of transient cerebral ischemia in the gerbil.

作者信息

Tomioka C, Nishioka K, Kogure K

机构信息

Department of Neurology, Tohoku University School of Medicine, Sendai, Japan.

出版信息

Acta Neuropathol. 1992;84(5):554-8. doi: 10.1007/BF00304475.

DOI:10.1007/BF00304475
PMID:1361091
Abstract

We examined changes in the tyrosine hydroxylase (TH)-immunoreactive fibers following 5 min of cerebral ischemia in gerbils using an immunohistochemical method 1, 3 and 30 days after ischemia. Almost all CA-1 pyramidal neurons were lost 3 days after ischemia, whereas noradrenergic fibers were maintained 30 days after ischemia. The present study demonstrated that TH-immunoreactive fibers and cells were resistant to transient ischemia, and that there was no sprouting or hyperactivity in noradrenergic systems after ischemia.

摘要

相似文献

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Resistance of hippocampal CA-1 noradrenergic fibers to five minutes of transient cerebral ischemia in the gerbil.
Acta Neuropathol. 1992;84(5):554-8. doi: 10.1007/BF00304475.
2
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本文引用的文献

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Reinnervation of the partially deafferented hippocampus by compensatory collateral sprouting from spared cholinergic and noradrenergic afferents.通过保留的胆碱能和去甲肾上腺素能传入神经的代偿性侧支发芽对部分传入神经切断的海马体进行再支配。
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Acta Neurol Scand. 1991 Nov;84(5):434-40. doi: 10.1111/j.1600-0404.1991.tb04984.x.
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